Alpha ketoacids

Alpha-ketoacids are a class of organic acids with a ketone group adjacent to a carboxylic acid, playing a central role in cellular energy metabolism. It features an isotopically labeled form of alpha-ketoglutarate, a key citric acid cycle intermediate, used as a tracer in metabolic flux studies. Sourcing this standard from a dedicated supplier means it arrives with verified identity, documented isotopic purity, and a certificate of analysis. This standard also supports analytical method development distinguishing a tracer from background metabolite levels.

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Isotope-Labeled Alpha-Ketoglutarate for Metabolic Research

A verified isotope-labeled standard matters most in tracer-based metabolic studies, where the accuracy of the isotopic label directly affects how confidently researchers can interpret flux data.

Clinivex supplies this labeled standard with a certificate of analysis, and our technical team can help source related isotopically labeled metabolites through our global supplier network for broader metabolic studies. If your study expands to track additional citric acid cycle intermediates alongside this one, our team can help identify related labeled standards that would pair well with it.

We’re ISO 9001:2015 and GMP certified and support academic and clinical research laboratories across the USA and Canada with accurate documentation for isotope-labeled tracers like this one.

This standard connects closely with the broader additional endogenous metabolites category, which covers a wider range of metabolic tracers. General metabolic research applications are a recurring subject within pharmaceutical and biotech research.

Contact our team to request a quote or check availability for this standard.

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    Frequently Asked Questions

    It’s a key intermediate in the citric acid cycle, the central pathway cells use to generate energy, making it a common target for metabolic tracer studies.

    A labeled version allows researchers to track how the compound moves through metabolic pathways using mass spectrometry, distinguishing it from naturally occurring, unlabeled molecules already present in a sample.

    Metabolic flux refers to the rate at which molecules move through a metabolic pathway, and studying it helps researchers understand how a cell’s energy production shifts under different conditions.

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