Stable Isotopes / Deuterated Compounds

High Isotopic Purity Deuterated Reference Standards for Mass Spectrometry and Quantitative Bioanalysis

Clinivex stocks an extensive range of deuterated reference standards spanning therapeutic drug classes, including analgesics, antidepressants, antipsychotics, antivirals, immunosuppressants, and oncology compounds, alongside deuterium-labelled environmental pollutants, pesticides, mycotoxins, and lipid mediators for non-clinical and regulatory testing applications. Each compound is synthesized to achieve high deuterium incorporation at chemically stable positions, minimizing back-exchange and ensuring consistent isotopic integrity throughout sample preparation, chromatographic separation, and ionization. Our catalog supports critical applications including plasma protein binding studies, metabolite identification, in vitro ADME profiling, forensic drug confirmation testing, and clinical therapeutic drug monitoring. For laboratories requiring a broader range of multi-isotope labels (¹³C, ¹⁵N, ¹⁸O), our stable isotope labelled standards catalog provides extensive coverage across all stable isotope types.

Every deuterated reference standard supplied by Clinivex is accompanied by a comprehensive Certificate of Analysis (CoA) documenting deuterium isotopic purity, chemical purity, solvent composition, and concentration – meeting the stringent expectations of FDA Bioanalytical Method Validation guidance, EMA BMV, ICH M10, and GLP study documentation requirements. Produced through ISO-compliant manufacturing processes by established synthetic chemistry partners, our deuterated standards provide the traceability and analytical credibility your method validation packages and regulatory dossiers require. Speak with our technical specialists to find the exact deuterated analogue your assay demands. Forensic and clinical toxicology laboratories will also benefit from our dedicated forensic toxicology reference standards portfolio covering opioids, fentanyl analogues, and NPS confirmatory testing.