Stable isotopes

Certified Stable Isotope Standards for Quantitative Research, Metabolic Studies, and Regulatory-Grade Analysis

Clinivex supplies stable isotope standards across a broad range of compound classes, including amino acids, fatty acids, steroids, vitamins, nucleosides, environmental contaminants, and pharmaceutical metabolites, enabling researchers and analytical scientists to build robust quantitative methods anchored by chemically matched internal references. In isotope dilution mass spectrometry (IDMS), widely regarded as a primary ratio measurement method by JCTLM and BIPM, these compounds serve as gold-standard tools for eliminating systematic bias in complex matrices such as serum, plasma, dried blood spots, and tissue extracts. Applications span newborn screening, vitamin D metabolite quantification, lipidomics, proteomics, stable isotope-resolved metabolomics (SIRM), and pharmacokinetic profiling. For workflows where deuterium labelling specifically is required, our deuterated reference standards catalog offers targeted d-labelled compounds across pharmaceutical, forensic, and environmental matrices.

Clinivex backs every stable isotope standard with a traceable Certificate of Analysis (CoA) that captures isotopic enrichment values, chemical purity, molecular confirmation, and recommended handling conditions, fully consistent with ISO 17511, JCTLM-listed reference measurement procedures, and applicable FDA and EMA regulatory expectations for method validation documentation. Our products are sourced from ISO-accredited synthesis facilities with established quality management systems, ensuring batch-to-batch consistency that your long-running studies and multi-site validation programs can depend on. Contact our scientific support team to discuss compound availability, custom concentration options, or solvent matrix preferences tailored to your specific workflow. For a broader suite of isotope-based internal standards, explore our stable isotope labelled standards portfolio spanning D, ¹³C, ¹⁵N, and ¹⁸O-labelled compounds across multiple compound classes.