Search by keyword, Catalog Number, CAS Number...
Search by keyword, Catalog Number, CAS Number...
Request quote

Stable isotopes

Stable isotope standards are compounds prepared with a defined, non-radioactive isotopic composition, used as reference points in analytical laboratory work. Because they’re chemically identical or closely related to naturally occurring compounds but carry a known isotopic signature, they can serve as reliable points of comparison in quantitative and analytical workflows. Clinivex supplies stable isotope standards for laboratories working across pharmaceutical, bioanalytical, and research settings. Browse the available products below, or contact our team to check availability for a specific compound.

Showing 1–16 of 64941 results

What Are Stable Isotope Standards Used For?

Stable isotope standards are commonly used in quantitative analytical workflows, particularly in mass spectrometry-based methods such as LC-MS/MS and GC-MS, where a known reference compound helps confirm identity or support accurate measurement. In some applications, a stable isotope standard may be used as part of an isotope dilution approach, where the known isotopic signature supports precise quantification of a target analyte. Depending on the specific compound and method, stable isotope standards can also support method development and validation work across pharmaceutical, bioanalytical, and related research applications. Not every application applies to every compound – the appropriate use depends on the specific standard and the analytical method being followed.

Types of Stable Isotope Standards

Stable isotope standards can be prepared using several different non-radioactive isotopes, including carbon-13 (¹³C), nitrogen-15 (¹⁵N), deuterium/hydrogen-2 (²H or D), and oxygen-18 (¹⁸O), depending on the specific compound and its intended analytical use. It’s worth noting that “stable isotope standards” and “stable isotope-labelled standards” are related but not always interchangeable terms – a labelled standard specifically refers to a compound synthesized to carry an isotopic label at a defined position, often for use as an internal standard, while “stable isotope standards” is a broader category that can include these alongside other isotopically defined reference materials. Not every stable isotope standard functions as an internal standard, and the specific role depends on the compound and method in question. For products designed specifically as isotope-labelled internal standards, our stable isotope labelled standards catalog may be a relevant related resource.

Read More

Types of Stable Isotope Standards
Assurance Where Service Meets Science

How to Choose an Isotope Labelled Reference Standard

The right standard depends on the analyte and the method. These points are worth checking before you order:

  • Label type. Deuterium-labelled standards are widely used, but deuterium can exchange with hydrogen under
    some conditions and may cause a small shift in retention time. 13C and 15N labels are generally more stable and tend
    to co-elute more closely with the analyte.
  • Label position. Where deuterium is used, it should sit on a non-exchangeable position of the molecule.
  • Mass difference. The standard should differ enough in mass from the native compound to avoid overlap with
    natural isotope peaks. A shift of at least three mass units is a common rule of thumb.
  • Match to the analyte. Where a labelled version of the exact compound you are measuring exists, it usually
    gives the closest correction.
  • Batch documentation. Review the Certificate of Analysis for the batch you receive and confirm that it meets
    your method requirements.

why Choose Clinivex?

At Clinivex, we earn trust by delivering impeccable service, expert guidance, and reliable solutions that drive long-term success. With a skilled team and customer-first approach, we stand as a leading pharmaceutical reference standards supplier in the USA and Canada.

dedicated-towards

Dedicated Towards Betterment

Driven by innovation, committed to progress.

one-stop-product

One-Stop Product Source

All-in-one destination for trusted scientific solutions.

where-trust-meet-innovation

Where Trust Meets Innovation

Blending trust, accuracy, and innovation for groundbreaking results.

fast-and-courteous

Fast and Courteous Customer Service

Merging reliability, accuracy, and innovation to redefine excellence.

Contact us

why Choose Clinivex
cta

Have questions? Get in touch!

Just fill in your details and our representatives will get back to you soon!

    Frequently Asked Questions

    “Stable isotope-labelled standards” specifically refers to compounds synthesized with an isotopic label at a defined position, often for use as an internal standard. “Stable isotope standards” is a broader term that can include these alongside other isotopically defined reference materials.

    Common examples include carbon-13 (¹³C), nitrogen-15 (¹⁵N), deuterium/hydrogen-2 (²H or D), and oxygen-18 (¹⁸O), depending on the compound and application.

    Yes, they’re frequently used in mass spectrometry-based methods such as LC-MS/MS and GC-MS, though the specific role depends on the compound and method.

    Yes, Clinivex supplies laboratories in 120+ countries.

    Join other members of the R&D community getting the latest news, information and guides.

    Join Our Mailing List